Fluvoxamine maleate is a selective SR (serotonin reputake) inhibitor. Fluvoxamine is described to bind the human 5-HT transporter protein with high affinity (Ki = 1.6 nM) while demonstrating very low affinity at the norepinephrine transporter (Ki = 2,950 nM). Fluvoxamine maleate is a Sigma Receptor agonist.