A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated.
PIMOZIDE
Structure
Product Description
Details |
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Chemical Name |
PIMOZIDE |
IUPAC Name |
1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazole-2-one |
CAS Number |
2062-78-2 |
Molecular Formula |
C28H29F2N3O |
Synonyms |
PIMOZIDE;1-(1-(4,4-bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinon;1-(1-(4,4-bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinone;1-(4,4-bis(p-fluorophenyl)butyl)-4-(2-oxo-1-benzimidazolinyl)piperidine;mcn-jr-6238;orap;1-[1-(4,4-BIS[4-FLUOROPHENYL]BUTYL)-4-PIPERIDINYL]-1,3-DIHYDRO-2H-BENZ-IMIDAZOL-2-ONE;3-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidyl)-1H-benzimidazol-2-one |
Application |
Used for the suppression of motor and phonic tics in patients with Tourette's Disorder who have failed to respond satisfactorily to standard treatment. |