A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Details |
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Chemical Name |
NALIDIXIC ACID |
IUPAC Name |
1-Ethyl-7-methyl-4-oxo-[1,8]naphthyridine-3-carboxylic acid |
CAS Number |
389-08-2 |
Molecular Formula |
C12H12N2O3 |
Synonyms |
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt |
Application |
For the treatment of urinary tract infections caused by susceptible gram-negative microorganisms, including the majority of E. Coli, Enterobacter species, Klebsiella species, and Proteus species. |