Loratadine is a non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells. Loratadine is a selective inverse peripheral histamine H1-receptor agonist (IC50 > 32 μM).
Loratadine
Structure
Product Description
Details |
|
|---|---|
Chemical Name |
Loratadine |
IUPAC Name |
Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate |
CAS Number |
79794-75-5 |
Molecular Formula |
C22H23CIN2O2 |
Synonyms |
Lisino;Tadine;Civeran;Loranox;CLARITIN;Clarityn;CLARATYNE;SCH-29851;Claritine;LORATADINE |
Application |
Anti-histamine |